Author/Authors :
Sirion، نويسنده , , Uthaiwan and Kim، نويسنده , , Hee-Jun and Lee، نويسنده , , Jae Hak and Seo، نويسنده , , Jai Woong and Lee، نويسنده , , Byoung Se and Lee، نويسنده , , Sang Ju and Oh، نويسنده , , Seung Jun and Chi، نويسنده , , Dae Yoon، نويسنده ,
Abstract :
The Cu(I)-catalyzed, 1,3-dipolar cycloaddition reaction was applied successfully to the synthesis of small, F-18-labeled biomolecules, and an optimal condition was developed for one-pot, two-step reaction without any interim purifications. This technique was employed in various F-18-labeled, 1,2,3-triazole syntheses with high radiochemical yield.