Title of article :
Sulfamic acid: an efficient, cost-effective and recyclable solid acid catalyst for the three-component synthesis of α-amino nitriles
Author/Authors :
Heydari، نويسنده , , Akbar and Khaksar، نويسنده , , Samad and Pourayoubi، نويسنده , , Mehrdad and Mahjoub، نويسنده , , Ali Reza، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
α-Amino nitriles are synthesized by the three-component coupling reaction of aldehydes, amines and trimethylsilyl cyanide using sulfamic acid as a heterogeneous solid acid catalyst, under solvent-free conditions in excellent yields. The catalyst was recovered by simple filtration and was recycled in subsequent reactions.
Keywords :
?-Amino nitriles , Sulfamic acid , Trimethylsilyl cyanide , Reusable
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters