Title of article
A novel, one-pot, three-component synthesis of 4H-pyrido[1,2-a]pyrimidines
Author/Authors
Adib، نويسنده , , Mehdi and Sayahi، نويسنده , , Mohammad Hosein and Nosrati، نويسنده , , Meisam and Zhu، نويسنده , , Long-Guan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
4195
To page
4198
Abstract
A novel, one-pot, three-component synthesis of 4H-pyrido[1,2-a]pyrimidines is described. The reactive 1:1 zwitterionic intermediate, formed by the addition of isocyanides to dialkyl acetylenedicarboxylates, was trapped by N-(2-pyridyl)amides to produce the title compounds under mild reaction conditions in good yields.
Keywords
Isocyanides , Acetylenic esters , Three-component synthesis , 2-a]pyrimidines , N-(2-Pyridyl)amides
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855191
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