Author/Authors :
Wang، نويسنده , , Chao and Jiang، نويسنده , , Yi and Zhang، نويسنده , , Xiaoxia and Huang، نويسنده , , Yi and Li، نويسنده , , Bo-gang and Zhang، نويسنده , , Guo-lin، نويسنده ,
Abstract :
A rationally designed organocatalyst for direct asymmetric aldol reaction in the presence of water has been developed. High yield (up to 99%), diastereoselectivity (up to 99:1) and enantioselectivity (up to 97%) were obtained under optimal conditions.
Keywords :
direct aldol reaction , organocatalysis , NOBIN , Asymmetric catalysis , water
