Title of article :
Microwave-assisted synthesis of mGluR1 ligands: carbon, nitrogen and oxygen linked derivatives of pyrido[3,4-d]pyrimidin-4-ylamines
Author/Authors :
Harbottle، نويسنده , , Gareth W. and Feeder، نويسنده , , Neil and Gibson، نويسنده , , Karl R. and Glossop، نويسنده , , Mel and Maw، نويسنده , , Graham N. and Million، نويسنده , , William A. and Morel، نويسنده , , Florence F. and Osborne، نويسنده , , Simon and Poinsard، نويسنده , , Cedric، نويسنده ,
Abstract :
The syntheses of 6-fluoropyrido[3,4-d]pyrimidin-4-ylamine derivatives is reported herein. Methods for generating C, N and O linked analogues under microwave irradiation are described.