Title of article
Water-soluble chiral monosulfonamide-cyclohexane-1,2-diamine-RhCp∗ complex and its application in the asymmetric transfer hydrogenation (ATH) of ketones
Author/Authors
Cortez، نويسنده , , Norma A. and Aguirre، نويسنده , , Gerardo and Parra-Hake، نويسنده , , Miguel and Somanathan، نويسنده , , Ratnasamy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
4335
To page
4338
Abstract
Monosulfonamide ligands with heteroatom/heterocyclic systems were derived from trans-(1R,2R)-cyclohexane-1,2-diamine and complexed with [Ru(benzene)Cl2]2, [Cp∗RhCl2]2 in situ and used in the ATH of aromatic ketones with aqueous sodium formate as the hydrogen source. The chiral secondary alcohols were obtained with >93% enantioselectivity and >89% yield. Reduction in water was faster than in isopropanol/KOH. Addition of surfactants showed little or no effects.
Keywords
RhCp? complex , ketones , Asymmetric transfer hydrogenation , Monosulfonamide ligands
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855247
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