Title of article
A fast and efficient bromination of isoxazoles and pyrazoles by microwave irradiation
Author/Authors
Li، نويسنده , , Guo and Kakarla، نويسنده , , Ramesh and Gerritz، نويسنده , , Samuel W.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
4595
To page
4599
Abstract
A fast and efficient method has been developed for the bromination of isoxazoles and pyrazoles using microwave irradiation. In this method, N-bromosuccinimide was used in different acid solvents according to the reactivity of the substrates to give mono-brominated isoxazoles and pyrazoles in good yields. Trifluoroacetic acid was found to be the best solvent for highly unreactive isoxazoles and pyrazoles.
Keywords
Pyrazole , Bromination , microwave , Isoxazole
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855381
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