Author/Authors :
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V.Subba and Padmavani، نويسنده , , B. and Venugopal، نويسنده , , Ch. and Rao، نويسنده , , A.Bhaskar، نويسنده ,
Abstract :
Enzymatic kinetic resolution of (±)-hydroxytetrahydropyrans has been achieved for the first time by means of lipase-mediated transesterification to afford optically active (2S,4R)-tetrahydropyranyl acetates and (2R,4S)-tetrahydropyranols in excellent yields with high enantioselectivity. Absolute configurations of the tetrahydropyranyl acetates were assigned as (S) by chemical correlation.
