Author/Authors :
Siberry، نويسنده , , George K. and Leister، نويسنده , , Erin and Jacobson، نويسنده , , Denise L. and Foster، نويسنده , , Samuel B. and Seage III، نويسنده , , George R. and Lipshultz، نويسنده , , Steven E. and Paul، نويسنده , , Mary E. and Purswani، نويسنده , , Murli and Colin، نويسنده , , Andrew A. and Scott، نويسنده , , Gwendolyn and Shearer، نويسنده , , William T.، نويسنده ,
Abstract :
The incidence of asthma and atopic dermatitis (AD) was evaluated in HIV-infected (n = 451) compared to HIV-exposed (n = 227) but uninfected (HEU) children and adolescents by abstraction from clinical charts. Asthma was more common in HIV-infected compared to HEU children by clinical diagnosis (25% vs. 20%, p = 0.101), by asthma medication use, (31% vs. 22%, p = 0.012), and by clinical diagnosis and/or medication use, (34% vs. 25%, p = 0.012). HIV-infected children had a greater risk of asthma compared to HEU children (HR = 1.37, 95% CI: 1.01 to 1.86). AD was more common in HIV-infected than HEU children (20% vs. 12%, p = 0.009)) and children with AD were more likely to have asthma in both cohorts (41% vs. 29%, p = 0.010). HIV-infected children and adolescents in this study had an increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide.
Keywords :
atopic dermatitis , asthma , Inhaled Corticosteroids , Protease inhibitors , pediatric HIV infection
