Title of article
Pot, atom and step economic (PASE) synthesis of highly functionalized piperidines: a five-component condensation
Author/Authors
Clarke، نويسنده , , Paul A. and Zaytzev، نويسنده , , Andrey V. and Whitwood، نويسنده , , Adrian C.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
5209
To page
5212
Abstract
The diastereoselective pot, atom and step economic (PASE) synthesis of highly functionalized piperidines has been realized. The procedure simply involves mixing methyl acetoacetate, 2 equiv of aldehyde and 2 equiv of aniline together in the presence of InCl3. In most cases the piperidine precipitates out of solution.
Keywords
piperidines , PASE , One-pot , Multi-component
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855699
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