Sequential cross-metathesis/phosphorus-based olefination: stereoselective synthesis of 2,4-dienoates

A variety of stereodefined 2,4-dienoates have been prepared in a stereoselective manner by sequencing olefin cross-metathesis (CM) with phosphorus-based olefination reactions (Wittig and Horner–Wadsworth–Emmons) in good yield using commercially available reagents.