Title of article
Sphenalactones A–D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera
Author/Authors
Xiao، نويسنده , , Wei-Lie and Yang، نويسنده , , Liu-Meng and Li، نويسنده , , Li-Mei and Pu، نويسنده , , Jian-Xin and Huang، نويسنده , , Sheng-Xiong and Weng، نويسنده , , Zhi-Ying and Lei، نويسنده , , Chun and Liu، نويسنده , , Jingping and Wang، نويسنده , , Rui-Rui and Zheng، نويسنده , , Yongtang and Li، نويسنده , , Rong-Tao and Sun، نويسنده , , Han-Dong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
5543
To page
5546
Abstract
Four novel highly oxygenated trinortriterpenoids, sphenalactones A–D (1–4), were isolated from the leaves and stems of Schisandra sphenanthera and their structures were elucidated by extensive analysis of 1D and 2D NMR data. Compounds 1–4 featured a C27 backbone and showed anti-HIV-1 activity with EC50 values in the range of 35.5–89.1 μg/mL with low cytotoxicity against C8166 cells (CC50 > 200 μg/mL).
Keywords
Sphenalactones A–D , Schisandra sphenanthera , Trinortriterpenoid , Anti-HIV activity
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855883
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