Author/Authors :
Nakamura، نويسنده , , Shuichi and Sano، نويسنده , , Hideaki and Nakashima، نويسنده , , Hiroki and Kubo، نويسنده , , Koji and Shibata، نويسنده , , Norio and Toru، نويسنده , , Takeshi، نويسنده ,
Abstract :
A catalytic enantioselective Mannich-type reaction of N-(2-pyridylsulfonyl)imines in the presence of chiral bis(oxazoline)s afforded the products with high enantioselectivity. Asymmetric induction was supposed to be efficiently controlled by a new chiral center on the sulfur dynamically induced through the discriminative coordination of a chiral Lewis acid to one of the sulfonyl oxygens.
