Title of article :
Sc(OTf)3-catalyzed alkylation of indoles with propargyl alcohols: an expeditious synthesis of 3-substituted indoles
Author/Authors :
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V. Subba and Rao، نويسنده , , K.V. Raghavendra and Kumar، نويسنده , , G.G.K.S. Narayana، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Indoles undergo smooth alkylation with propargylic alcohols in the presence of 10 mol % of scandium triflate under mild conditions to produce 3-propargylated indoles in excellent yields with high selectivity.
Keywords :
Alkylation , indoles , propargyl alcohols , scandium(III) triflate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters