Author/Authors :
Stepanenko، نويسنده , , Viatcheslav and Jesْs، نويسنده , , Melvin De and Correa، نويسنده , , Wildeliz and Guzmلn، نويسنده , , Irisbel and Vلzquez، نويسنده , , Cindybeth and de la Cruz، نويسنده , , Wilanet and Ortiz-Marciales، نويسنده , , Margarita and Barnes، نويسنده , , Charles L.، نويسنده ,
Abstract :
Novel spiroborate esters derived nonracemic 1,2-aminoalcohols and ethylene glycol are reported as highly effective catalysts for the asymmetric borane reduction of a variety of prochiral ketones with borane–dimethyl sulfide complex at room temperature. Optically active alcohols were obtained in excellent chemical yields using 0.1–10 mol % of catalysts with up to 99% ee.
