Synthesis of a fluoroalkene peptidomimetic precursor of N-acetyl-l-glutamyl-l-alanine
Author/Authors :
Lamy، نويسنده , , Carole and Hofmann، نويسنده , , Johann and Parrot-Lopez، نويسنده , , Hélène and Goekjian، نويسنده , , Peter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Pages :
4
From page :
6177
To page :
6180
Abstract :
Fluoroolefin peptidomimetics of the dipeptide N-acetyl-Glu-Ala were synthesized via an Evans asymmetric aldol reaction and an Overman rearrangement. This dipeptide is the N-terminal of an octapeptide implicated in the signal transduction via PKCε.