Author/Authors :
Kysil، نويسنده , , Volodymyr and Tkachenko، نويسنده , , Sergey and Khvat، نويسنده , , Alexander and Williams، نويسنده , , Caroline and Tsirulnikov، نويسنده , , Sergey V. Churakova، نويسنده , , Marina and Ivachtchenko، نويسنده , , Alexandre، نويسنده ,
Abstract :
New trimethylchlorosilane (TMSCl) promoted multicomponent reaction (MCR) of ethylenediamine(s), diverse carbonyl compounds, and isocyanides is proposed for the synthesis of a variety of highly substituted 3,4,5,6-tetrahydropyrazin-2-amines including corresponding spirocyclic compounds.
Keywords :
Multicomponent reaction (MCR) , isocyanide , Pyrazine ring synthesis , Trimethylchlorosilane (TMSCl) , Aminopyrazine