Title of article
HClO4–SiO2 catalyzed stereoselective synthesis of β-amino ketones via a direct Mannich-type reaction
Author/Authors
Bigdeli، نويسنده , , Mohammad A. and Nemati، نويسنده , , Firouzeh and Mahdavinia، نويسنده , , Gholam Hossien، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
6801
To page
6804
Abstract
The HClO4–SiO2 catalyzed three-component, one-pot Mannich reaction of ketones, aromatic aldehydes and aromatic amines is carried out in ethanol to afford the corresponding β-amino ketones in good yields and high stereoselectivities in favor of the anti-isomer. Three new compounds are reported.
Keywords
Mannich reaction , ?-amino ketones , stereoselective , Silica perchloric acid
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856574
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