Title of article
Domino Knoevenagel/Diels–Alder sequence coupled to Suzuki reaction: a valuable synthetic platform for chemical biology
Author/Authors
Pizzirani، نويسنده , , Daniela and Roberti، نويسنده , , Marinella and Recanatini، نويسنده , , Maurizio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
7120
To page
7124
Abstract
A small library of peculiar biphenyl and terphenyl-containing spirocyclic triones has been synthesized in parallel by combining the organocatalytic three-component domino Knoevenagel/Diels–Alder sequence to Suzuki coupling. This methodology is fast, general and serves as a platform to gain access to novel chemical tools to probe protein–protein interactions.
Keywords
Chemical biology , Multi-component reaction , Domino process , Biasing element , Spiro compound
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856685
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