Title of article :
Stereoselective total synthesis of arenastatin A, a spongean cytotoxic depsipeptide
Author/Authors :
Kotoku، نويسنده , , Naoyuki and Narumi، نويسنده , , Fuminori and Kato، نويسنده , , Tomoya and Yamaguchi، نويسنده , , Miho and Kobayashi، نويسنده , , Motomasa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
A highly stereoselective total synthesis of arenastatin A, an extremely potent cytotoxic cyclic depsipeptide from marine sponge, was developed. The desired 7,8-β-epoxide in arenastatin A was constructed by asymmetric sulfur ylide-mediated epoxidation in good yield and highly stereoselective manner.
Keywords :
Arenastatin A , depsipeptide , total synthesis , Asymmetric epoxidation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
