Author/Authors :
Kumar، نويسنده , , Amit and Singh، نويسنده , , Fateh V. and Goel، نويسنده , , Atul، نويسنده ,
Abstract :
A regioselective synthesis of unsymmetrical biaryls with electron withdrawing or donating substituents is described and illustrated by carbanion-induced ring transformation of 6-aryl-α-pyrones with methoxyacetone in excellent yield. Our methodology is an alternative to classical organometal-catalyzed aryl–aryl coupling reactions and can be applied to the synthesis of functionally demanding naphthyl biaryls for the development of new ligands for asymmetric synthesis.
