An improved procedure for the separation of (+) or (−)-isopinocampheol, the major side product of the oxidation workup procedure of Brown’s asymmetric crotylborations

Separation of (+) or (−)-isopinocampheol, the major side product of the oxidation workup procedure of Brown’s asymmetric reactions such as crotylborations from the desired product is quite tedious and often requires repeated column chromatography. It is discovered that a sublimation process can be used to easily separate this major side product.