An easy one-pot stereoselective synthesis of 4-substituted and 4,5-disubstituted oxazolidin-2-ones from N-Boc-2,3-aziridino alcohols

A novel and efficient one-pot stereoselective transformation of N-(t-butoxycarbonyl)-2,3-aziridino alcohols into 4-substituted and 4,5-disubstituted oxazolidin-2-ones has been developed; these functionalized products are amenable to other elaborations, some of which are described.