Title of article :
A convenient synthesis of 1,2,4-trisubstituted azetidines by reductive cyclization of aza-Michael adducts of chalcones
Author/Authors :
Yadav، نويسنده , , Lal Dhar S. and Awasthi، نويسنده , , Chhama and Rai، نويسنده , , Vijai K. and Rai، نويسنده , , Ankita، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Aza-Michael adducts of chalcones and diethyl N-arylphosphoramidates undergo reductive cyclization with sodium borohydride followed by sodium hydride to afford 1,2,4-trisubstituted azetidines diastereoselectively in a one-pot procedure and excellent yields.
Keywords :
azetidines , Michael addition , Chalcones , Phosphoramidates , Reduction , Cyclization reactions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
