Title of article
The first example of the C-3 alkylation of indoles with cyclopropyl ketones promoted by CeCl3·7H2O/LiI
Author/Authors
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V. Subba and Chandrakanth، نويسنده , , D. and Satheesh، نويسنده , , G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
8040
To page
8042
Abstract
Indoles undergo smooth alkylation with cyclopropyl ketones in the presence of the CeCl3·7H2O/LiI reagent system in refluxing acetonitrile under neutral conditions to produce the corresponding C-3 substituted indole derivatives in good to high yields and with high selectivity. The use of CeCl3·7H2O/LiI makes this method simple, convenient, and cost-effective.
Keywords
indoles , cerium(III) compounds , Activated cyclopropanes , C-3 alkylation
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857196
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