Title of article :
Asymmetric synthesis of (+)-iso-6-cassine via stereoselective intramolecular amidomercuration
Author/Authors :
Singh، نويسنده , , Satwinder and Singh، نويسنده , , Om V. and Han، نويسنده , , Hyunsoo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
The first asymmetric synthesis of (+)-iso-6-cassine is described. Lipase-catalyzed resolution, enantioselective Overman rearrangement, and diastereoselective intramolecular amidomercuration were used for the installation of the three stereocenters in (+)-iso-6-cassine, and cross-metathesis was employed for the attachment of the side-chain.
Keywords :
2 , Intramolecular amidomercuration , 6-Dialkylpiperidines , 6-Disubstituted 3-piperidinols , 2 , (+)-iso-6-Cassine , double stereodifferentiation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
