Title of article :
A facile non-oxidative method for synthesizing 1,3-disubstituted pyrroles from pyrrolidine and aldehydes
Author/Authors :
Oda، نويسنده , , Mitsunori and Fukuchi، نويسنده , , Yosuke and Ito، نويسنده , , Satoshi and Thanh، نويسنده , , Nguyen Chung and Kuroda، نويسنده , , Shigeyasu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
Reactions of pyrrolidine with 2 equiv of aldehydes without any catalyst in a pressurized vessel at 140–200 °C yielded 1,3-disubstituted pyrroles. α-Branched aldehydes gave fairly good yields of the corresponding products by this method, which provides a facile non-oxidative procedure for synthesizing 1,3-dialkylpyrroles from inexpensive pyrrolidine and aldehydes.
Keywords :
pyrrole , pyrrolidine , aldehyde , Enamine , Hydride shift
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
