Title of article :
Intermolecular coupling of alkynes, isocyanates, and acyl chlorides: an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones
Author/Authors :
Kanno، نويسنده , , Ken-ichiro and Ren، نويسنده , , Shenyong and Li، نويسنده , , Yanzhong and Nakajima، نويسنده , , Kiyohiko and Takahashi، نويسنده , , Tamotsu، نويسنده ,
Abstract :
New insights into the reaction of diethylzirconocene with an alkyne, an isocyanate, and an acyl chloride in this order are reported. The products of 5-hydroxypyrrol-2(5H)-ones are obtained in good yields after hydrolysis. It is an efficient method for the synthesis of 5-hydroxypyrrol-2(5H)-ones.