Author/Authors :
Thiel، نويسنده , , Oliver R. and Bernard، نويسنده , , Charles and Tormos، نويسنده , , Wanda and Brewin، نويسنده , , Alan and Hirotani، نويسنده , , Shuji and Murakami، نويسنده , , Kazuo and Saito، نويسنده , , Kenji and Larsen، نويسنده , , Robert D. and Martinelli، نويسنده , , Michael J. and Reider، نويسنده , , Paul J.، نويسنده ,
Abstract :
A practical synthesis of cinacalcet (Sensipar®, Mimpara®) is described. The synthesis starts from readily available starting materials and relies on safe and practical reaction conditions. The sequence comprises three synthetic steps and only one isolation point. The overall yield for the sequence is 85%.
