• Title of article

    Transesterifications mediated by t-BuNH2

  • Author/Authors

    Suلrez-Castillo، نويسنده , , Oscar R. and Montiel-Ortega، نويسنده , , Luis Alberto and Fragoso-Vلzquez، نويسنده , , Manuel Jonathan and Meléndez-Rodrيguez، نويسنده , , Myriam and Sلnchez-Zavala، نويسنده , , Maricruz، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    996
  • To page
    999
  • Abstract
    A mild protocol for transesterification of simple esters is described. The method is based on the use of t-BuNH2/ROH (R = Me, Et, i-Pr, t-Bu) with or without LiBr. The scope of the procedure was explored for aliphatic and aromatic esters. The protocol is particularly useful when going from higher to lower hindered esters and harsh reaction conditions are needed for the reversal process. A rationalization of the mechanism is presented. The scope and limitation of this transformation are also described.
  • Keywords
    tert-Butylamine , Transesterification , Lithium Bromide , Aliphatic esters , Aromatic esters
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1858130