Title of article :
Hexabromoacetone and ethyl tribromoacetate: a highly efficient reagent for bromination of alcohol
Author/Authors :
Pratoomrat Tongkate، نويسنده , , Pratoomrat and Pluempanupat، نويسنده , , Wanchai and Chavasiri، نويسنده , , Warinthorn، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A new and efficient method for the bromination of alcohols utilizing Br3CCOCBr3/PPh3 and Br3CCO2Et/PPh3 is described. Various alcohols can be converted smoothly into their corresponding alkyl bromides in high yields under mild conditions with short reaction times. Based upon 1H NMR studies using competitive reactions between selected brominating agents and Cl3CCN, Br3CCOCBr3 displays the highest reactivity approximately nine times that of CBr4.
Keywords :
Hexabromoacetone , alcohols , Bromination , Triphenylphosphine , Ethyl tribromoacetate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
