Title of article
A facile and efficient one-pot synthesis of thiirans by the reaction of benzoxazolyl β-ketosulfides with NaBH4/NaOH
Author/Authors
Yamada، نويسنده , , Nobuhiko and Mizuochi، نويسنده , , Masayoshi and Takeda، نويسنده , , Masahiro and Kawaguchi، نويسنده , , Hiroyuki and Morita، نويسنده , , Hiroyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
1166
To page
1168
Abstract
Convenient and efficient procedures for thiirans have been developed via a one-pot reaction of benzoxazolyl β-ketosulfides with NaBH4 and NaOH in MeOH and THF. The reaction is considered to proceed via the spiro intermediate by the ipso-addition of β-hydroxygroup, which is formed by the NaBH4 reduction of β-keto group, to 2-position of benzoxazole group.
Keywords
Thiirans , ?-Ketosulfides , one-pot synthesis , benzoxazole
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858209
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