Author/Authors :
Szabَ، نويسنده , , Zoltلn B. and Borbلs، نويسنده , , Anikَ and Bajza، نويسنده , , Istvلn and Liptلk، نويسنده , , Andrلs and Antus، نويسنده , , Sلndor، نويسنده ,
Abstract :
Sulfonic acid analogues of N-acetylneuraminic are synthesized from 1-thio-l-fucoside derivatives with the introduction of an azido group at C-4 of the fucose moiety and carbanionic addition onto fully protected lactones. The analogues in the form of methyl glycosides are subjected to a neuraminidase inhibition assay.
Keywords :
N-Acetylneuraminic acid analogues , Thioglycosides , Methyl glycosides , Sulfonic acids
