Author/Authors :
Lee، نويسنده , , Han Na and Kim، نويسنده , , Ha Na and Swamy، نويسنده , , K.M.K. and Park، نويسنده , , Min-Sun and Kim، نويسنده , , Jimi and Lee، نويسنده , , Hyunsook and Lee، نويسنده , , Keun-Hyeung and Park، نويسنده , , Sungsu and Yoon، نويسنده , , Juyoung، نويسنده ,
Abstract :
Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg2+ and Cd2+ in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg2+ or Cd2+ among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg2+ and Cd2+ ions in mammalian cells.
