Author/Authors :
Momose، نويسنده , , Takayuki and Hama، نويسنده , , Naoto and Higashino، نويسنده , , Chiharu and Sato، نويسنده , , Hideyuki and Chida، نويسنده , , Noritaka، نويسنده ,
Abstract :
The chiral and stereoselective total synthesis of A-315675 1, an antiinfluenza agent, is described. The vicinal diamino moiety in 1 was stereoselectively constructed by the cascade Overman rearrangement of a vicinal allylic-homoallylic diol derived from d-tartrate.
Keywords :
A-315675 , total synthesis , Cascade Overman rearrangement , Antiinfluenza agent
