Author/Authors :
Shi، نويسنده , , Qinghua and Lee، نويسنده , , Yeon Ju and Kim، نويسنده , , Mi-Jeong and Park، نويسنده , , Mi-Kyung and Lee، نويسنده , , Kyoungyim and Song، نويسنده , , Hongrui and Cheng، نويسنده , , Maosheng and Jeong، نويسنده , , Byeong-Seon and Park، نويسنده , , Hyeung-geun and Jew، نويسنده , , Sang-sup، نويسنده ,
Abstract :
Merrifield resin supported cinchona ammonium salts bearing 2′-fluorobenzene, 2′-cyanobenzene and 2′-N-oxypyridine groups were prepared and applied to the phase-transfer catalytic alkylation of N-(diphenylmethylene)glycine tert-butyl ester for the enantioselective synthesis of α-amino acids (76–96% ee).
Keywords :
Phase-transfer catalyst , enantioselective synthesis , Polymer-supported catalyst , Cinchona alkaloid
