Title of article :
Synthesis of RHPS4 via an anionic ring closing cascade
Author/Authors :
Kristensen، نويسنده , , Jesper Langgaard Kristensen، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A new and convergent synthesis of the potent telomerase inhibitor RHPS4 is presented. The key step is the construction of the pentacyclic framework via an anionic ring closing cascade in which two new rings are formed.
Keywords :
cyclizations , antitumour agents , Fused-ring systems , Nucleophilic aromatic substitutions , ring closure
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
