Author/Authors :
Sato، نويسنده , , Kosuke and Kuriyama، نويسنده , , Masami and Shimazawa، نويسنده , , Rumiko and Morimoto، نويسنده , , Tsumoru and Kakiuchi، نويسنده , , Kiyomi and Shirai، نويسنده , , Ryuichi، نويسنده ,
Abstract :
Direct aldol reactions of several aromatic aldehydes with ketones using l-proline-2,4,6-trinitroanilide catalyst 2d were conducted. Under optimized conditions, high enantioselectivity (99% ee), regioselectivity (up to 95:5), and diastereoselectivity (up to 98:2) were achieved.
