Title of article
First heterogeneously palladium-catalysed fully selective C3-arylation of free NH-indoles
Author/Authors
Cusati، نويسنده , , Giuseppe and Djakovitch، نويسنده , , Laurent، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
2499
To page
2502
Abstract
A simple heterogeneously palladium-catalysed procedure for the selective C3-arylation of indoles is reported. Under relatively standard reaction conditions (Pd-catalyst, K2CO3, dioxane, reflux), using only 1 mol % [Pd(NH3)4]/NaY as the catalyst, indoles substituted or not at position 2 gave up to 92% conversion (i.e., 85% isolated yield) towards the expected C3-arylated indole.
Keywords
indoles , Selective C3-arylation , Heterogeneous catalysis , PALLADIUM
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858887
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