Title of article
Simultaneous reduction of nitro- to amino-group in the palladium-catalyzed Suzuki cross-coupling reaction
Author/Authors
Wang، نويسنده , , Heng-Shan and Wang، نويسنده , , Ying-Chun and Pan، نويسنده , , Ying-Ming and Zhao، نويسنده , , Shulin and Chen، نويسنده , , Zhen-Feng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
2634
To page
2637
Abstract
An efficient method for palladium-catalyzed Suzuki cross-coupling reaction with simultaneous reduction of nitro- to amino-group has been developed. This method allows nitro-substituted aryl halides to readily react with arylboronic acids, to afford aryl substituted aniline in low to excellent yields. The reaction was catalyzed by Pd(OAc)2 (3 mol %) at 150 °C under atmospheric pressure in the presence of K2CO3 (3 equiv) in DMF/H2O (5/1).
Keywords
PALLADIUM , Suzuki cross-coupling , Reduction , Aryl substituted aniline
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858951
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