Title of article
Simple synthesis of fresh alkyl iodides using alcohols and hydriodic acid
Author/Authors
Klein، نويسنده , , Suzane M. and Zhang، نويسنده , , Cungen and Jiang، نويسنده , , Yu Lin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
2638
To page
2641
Abstract
A simple synthesis of fresh alkyl iodides using alcohols and hydriodic acid (HI) is reported. The alkyl iodides were obtained in quick and easy work-up with good to excellent yields (66–94%) and very high purities (97–99%). Freshly prepared iodomethane and 1-iodobutane were applied to synthesize biologically relevant 3,7-dimethyladenine and 9-butyladenine, which were characterized thoroughly using 1D and 2D NMR, individually.
Keywords
alcohols , Hydrogen bromide , Hydriodination , Hydrobromination , alkyl iodides , Alkyl bromides , Hydriodic acid
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858953
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