Title of article
A tandem Ferrier and Click reaction: a facile synthesis of triazolyl-2,3-dideoxypyranosides
Author/Authors
Yadav، نويسنده , , J.S. and Reddy، نويسنده , , B.V. Subba and Chary، نويسنده , , D. Narasimha and Reddy، نويسنده , , Ch. Suresh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
2649
To page
2652
Abstract
Glycosyl azides, prepared in situ from glucal and trimethylsilyl azide via Ferrier rearrangement, undergo smooth coupling with alkynes under neutral conditions by means of ‘Click reactions’ to furnish 1,2,3-triazole-linked glycoconjugates in high yields and with moderate stereoselectivity. The method provides a convenient route to prepare glycoconjugates from glucals, trimethylsilyl azide, and alkynes via a three component reaction.
Keywords
Triazoles , Click reaction , Alkynes , Glycoconjugates , glucal
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858960
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