Stereoselective synthesis of novel (R)- and (S)-5-azidomethyl-2-oxazolidinones from (S)-epichlorohydrin: a key precursor for the oxazolidinone class of antibacterial agents
Author/Authors :
Madhusudhan، نويسنده , , G. and Om Reddy، نويسنده , , G. and Rajesh، نويسنده , , T. and Ramanatham، نويسنده , , J. and Dubey، نويسنده , , P.K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Pages :
3
From page :
3060
To page :
3062
Abstract :
A facile synthesis of novel (R)- and (S)-5-azidomethyl-2-oxazolidinones starting from (S)-epichlorohydrin is described. The (R)-azide was utilized for the preparation of Linezolid.
