Title of article
PEG-400 as green reaction medium for Lewis acid-promoted cycloaddition reactions with isoeugenol and anethole
Author/Authors
Kouznetsov، نويسنده , , Vladimir V. and Merchan Arenas، نويسنده , , Diego R. and Romero Bohَrquez، نويسنده , , Arnold R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
3097
To page
3100
Abstract
A simple and efficient one-pot method for the synthesis of new 2,4-diaryl-1,2,3,4-tetrahydroquinolines using a three-component imino Diels–Alder cycloaddition between trans-isoeugenol or trans-anethole, anilines, and benzaldehyde in the presence of BF3·OEt2 in PEG-400, a green and reusable solvent, has been developed. Also, BF3·OEt2-catalyzed formal [3+2] cycloaddition reaction of trans-isoeugenol or trans-anethole with 1,4-benzoquinone in PEG-400 to give dihydrobenzo[b]furan derivatives has been described.
Keywords
Multi-component reaction , Imino Diels–Alder reaction , 3-Dihydrobenzofuran-5-ols , 2 , trans-Isoeugenol , tetrahydroquinolines , trans-Anethole , Benzoquinone , Polyetilenglicol (PEG-400)
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859162
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