• Title of article

    Nucleophilic fluoroalkylation of iminium salts

  • Author/Authors

    Levin، نويسنده , , Vitalij V. and Kozlov، نويسنده , , Mikhail A. and Song، نويسنده , , Young-Hun and Dilman، نويسنده , , Alexander D. and Belyakov، نويسنده , , Pavel A. and Struchkova، نويسنده , , Marina I. and Tartakovsky، نويسنده , , Vladimir A.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    3108
  • To page
    3111
  • Abstract
    Iminium cations generated by the coupling of aldehydes, N-trimethylsilylamines and TMSOTf or by the methylation of imines with MeOTf smoothly react with silanes of a general formula Me3SiRf (Rf = CF3, CCl2F, C6F5) to afford the corresponding tertiary amines having a fluorinated substituent. The key step, involving C–C bond formation, is promoted by NaOAc or KF in DMF as a solvent.
  • Keywords
    Iminium ions , imines , Lewis bases , Fluorinated silanes
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1859171

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1859171