Title of article
The synthesis of new, selected analogues of the pro-apoptotic and anticancer molecule HA 14-1
Author/Authors
Grée، نويسنده , , Danielle and Vorin، نويسنده , , Samuel and Manthati، نويسنده , , Vijay L. and Caijo، نويسنده , , Frédéric and Viault، نويسنده , , Guillaume and Manero، نويسنده , , Florence and Juin، نويسنده , , Philippe and Grée، نويسنده , , René، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
3276
To page
3278
Abstract
A new and versatile strategy has been developed towards HA 14-1 analogues, selectively modified on position 4 and/or on the primary amine function. An important aspect was the appropriate selection of the phenol protective group in the 5-bromosalicylaldehyde, allowing the isolation of the key intermediate the 2H-benzopyrane-2-imine 2′.
Keywords
HA 14-1 , bcl-2 , Anticancer , Benzopyrane
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859239
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