Title of article :
Phenyl-EDOTn derivatives as super acid labile carboxylic acid protecting groups for peptide synthesis
Author/Authors :
Isidro-Llobet، نويسنده , , Albert and ءlvarez، نويسنده , , Mercedes and Albericio، نويسنده , , Fernando، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
A series of new 3,4-ethylenedioxy-2-thenyl (EDOTn) derived alcohols have been synthesized and evaluated as super acid labile carboxylic acid protecting groups. All the derivatives are labile to very low concentrations of TFA (0.01–0.5%).
Keywords :
Acid labile protecting groups , Carboxylic acid protection , peptide synthesis , EDOTn , EDOT
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
