Title of article
A tandem palladium-catalyzed Heck-lactonization through the reaction of ortho-iodophenols with β-substituted acrylates: synthesis of 4,6-substituted coumarins
Author/Authors
Fernandes، نويسنده , , Talita de A. and Carvalho، نويسنده , , Rita de C.C. and Gonçalves، نويسنده , , Tatiana M.D. and da Silva، نويسنده , , Alcides J.M. and Costa، نويسنده , , Paulo R.R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
3322
To page
3325
Abstract
Coumarins were obtained in one pot through a palladium-catalyzed Heck-lactonization reaction involving ortho-iodophenols and methyl crotonate or a Z-enoate derived from d-mannitol. These reactions were investigated under different conditions and palladium sources. In the more interesting cases, coumarins were prepared in water, using triethylamine as base and 1 mol % of PdCl2 as catalyst.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859264
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