Title of article
Hydrogen bond catalyzed chemoselective N-tert-butoxycarbonylation of amines
Author/Authors
Khaksar، نويسنده , , Samad and Heydari، نويسنده , , Akbar and Tajbakhsh، نويسنده , , Mahmood and Vahdat، نويسنده , , Seyed Mohammad، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
3527
To page
3529
Abstract
A novel, chemoselective mono-N-Boc protection of various structurally diverse amines with di-tert-butoxypyrocarbonate (Boc)2O is described that relies on selective carbonyl activation by hydrogen bond formation. This mild, acid- and metal-free process requires only catalytic amounts of thiourea as hydrogen bond donor.
Keywords
Amines , (Boc)2O , Thiourea , Hydrogen bonding , Chemoselective
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859353
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