Title of article
One-pot three-component synthesis of pyrazoles through a tandem coupling-cyclocondensation sequence
Author/Authors
Liu، نويسنده , , Hai-Ling and Jiang، نويسنده , , Huanfeng and Zhang، نويسنده , , Min and Yao، نويسنده , , Wenjuan and Zhu، نويسنده , , Qiu-Hua and Tang، نويسنده , , Zhou، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
3805
To page
3809
Abstract
An efficient and general one-pot procedure for the synthesis of pyrazoles from acid chlorides, terminal alkynes and hydrazines was described via a coupling and cyclocondensation sequence. Acid chlorides coupled with terminal alkynes to give α,β-unsaturated ynones, and in situ converted into pyrazoles by the cycloaddition of hydrazines. The desired pyrazoles were obtained with 15–85% isolated yields.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859478
Link To Document